What causes a stitch when running?
The medical name is exercise-related transient abdominal pain (ETAP), and despite how common it is — surveys find most runners experience it — the cause is still not settled. Several explanations have been proposed and the evidence points most strongly at one.
The leading theory is irritation of the parietal peritoneum, the membrane lining the abdominal cavity. Friction between its layers, aggravated by movement and by a full or distended stomach, would explain most of the observed pattern: why the pain is sharp and well localised, why it is worse in activities with repetitive torso movement such as running and horse riding, and why it often refers to the shoulder tip, which shares nerve supply with the diaphragm region.
The older diaphragm-ischaemia theory — that the diaphragm is starved of blood during hard effort — has fallen out of favour, since it does not fit the evidence well.
What is well established are the risk factors:
Eating or drinking shortly before exercise, particularly large volumes and especially high-sugar or concentrated drinks. This is the strongest and most consistent finding.
Being younger — ETAP becomes less common with age.
Poor training status, though experienced athletes still get it.
Spinal posture, with some association found for particular curvature patterns.
What to do in the moment: slow down, breathe deeply, and press or bend forward on the affected side. Tightening the abdominal muscles while exhaling forcefully helps some people.
Prevention: avoid large meals in the two to three hours before running, limit concentrated drinks during exercise, and build intensity gradually.
Seek medical advice if abdominal pain during exercise is severe, persists after stopping, occurs with chest pain, breathlessness or nausea, or is a new symptom in someone over 40 — chest and upper abdominal pain on exertion can have cardiac causes.