Why do onions make you cry?
Because a cut onion manufactures an airborne irritant on the spot, as a chemical defence, and your eyes react to it before you notice anything.
An intact onion is harmless. Its cells keep sulphur-containing compounds in one compartment and an enzyme called alliinase in another. Cutting ruptures the cell walls and lets them mix. A second enzyme, unique to onions and their close relatives, then converts the products into a small volatile molecule, syn-propanethial-S-oxide. That molecule drifts up from the board and reaches the surface of your eyes.
There it dissolves in the film of moisture on the cornea, forming a weak acid and stimulating nerve endings that report chemical irritation. Your tear glands respond exactly as they would to grit or smoke, by flushing the surface. The stinging is a genuine irritation response, not an emotional one, which is why it is entirely involuntary and why some people are far more sensitive than others.
The practical implications follow directly from the chemistry. The reaction needs ruptured cells, so a sharp knife that slices rather than crushes releases less. The compound is volatile, so chilling the onion for fifteen minutes before cutting slows its escape into the air. It is water-soluble, so cutting near a running tap or under an extractor fan carries it away. And since it has to reach your eyes, simply keeping your face further from the board — or wearing sealed goggles, which genuinely works — prevents the whole thing.
The old advice about holding a spoon in your mouth or cutting while facing a flame has no reliable evidence behind it. Ventilation, a sharp knife and distance are the measures that actually address the mechanism.