What does bioavailability mean in nutrition?
The proportion of a nutrient that is actually absorbed and available for use — as distinct from the amount present in the food. It is why the number on a label can substantially overstate what you receive, and why some nutrients need more thought than a total suggests.
Why absorption varies so much:
The chemical form. Haem iron from meat is absorbed at a far higher rate than non-haem iron from plants, which is the single clearest example. Different forms of the same mineral in supplements also differ.
What it is eaten with. Some combinations help and some hinder:
Vitamin C markedly increases non-haem iron absorption.
Fat is required for vitamins A, D, E and K, so a salad eaten without any fat delivers less than it appears to.
Phytates in wholegrains and legumes and oxalates in spinach bind minerals and reduce absorption — which is why spinach is a poor calcium source despite the content.
Tannins in tea and coffee reduce iron absorption when drunk with a meal.
Calcium and iron compete, so large doses together reduce both.
Processing and preparation. Cooking, soaking, sprouting and fermenting all reduce anti-nutrients and raise availability. Cooking increases lycopene availability from tomatoes while reducing vitamin C — so there is no single "better" preparation.
The body's own status. Absorption is regulated: iron uptake rises when stores are low, and calcium absorption is more efficient when intake is low.
Age and gut health, both of which reduce absorption of several nutrients — B12 particularly, where stomach acid and intrinsic factor are required.
What follows practically:
Plant-based diets need attention to iron, zinc, B12, omega-3 and calcium — not because the diet is deficient by nature, but because availability differs.
Pair strategically, and separate competing nutrients.
Be sceptical of supplement content claims when the form is not stated.
General information, not dietary advice.